Detalhe da pesquisa
1.
The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3ß in myeloma by atypical K63-linked polyubiquitination.
J Biol Chem
; 299(5): 104675, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37028761
2.
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
J Biol Chem
; 298(9): 102314, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35926709
3.
Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma.
Blood
; 137(11): 1478-1490, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32842143
4.
RP58 knockdown contributes to hypoxia-ischemia-induced pineal dysfunction and circadian rhythm disruption in neonatal rats.
J Pineal Res
; 75(1): e12885, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37183291
5.
Inhibition of USP10 induces myeloma cell apoptosis by promoting cyclin D3 degradation.
Acta Pharmacol Sin
; 44(9): 1920-1931, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37055530
6.
The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.
J Biol Chem
; 297(3): 101088, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34416231
7.
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer.
Acta Pharmacol Sin
; 43(3): 681-691, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33931764
8.
The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.
J Biol Chem
; 295(7): 2084-2096, 2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31822558
9.
Glaucocalyxin A suppresses multiple myeloma progression in vitro and in vivo through inhibiting the activation of STAT3 signaling pathway.
Cancer Cell Int
; 21(1): 683, 2021 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923957
10.
Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis.
Cell Commun Signal
; 19(1): 24, 2021 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33627137
11.
Inhibition of the deubiquitinase USP9x induces pre-B cell homeobox 1 (PBX1) degradation and thereby stimulates prostate cancer cell apoptosis.
J Biol Chem
; 294(12): 4572-4582, 2019 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718275
12.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Acta Pharmacol Sin
; 41(3): 394-403, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31645658
13.
The transmembrane protein TMEPAI induces myeloma cell apoptosis by promoting degradation of the c-Maf transcription factor.
J Biol Chem
; 293(16): 5847-5859, 2018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467225
14.
Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis.
Acta Pharmacol Sin
; 40(12): 1568-1577, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31197245
15.
The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice.
Blood
; 127(13): 1676-86, 2016 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26825710
16.
A novel hedgehog inhibitor for the treatment of hematological malignancies.
Anticancer Drugs
; 29(10): 995-1003, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30106753
17.
The Ring Finger Protein RNF6 Induces Leukemia Cell Proliferation as a Direct Target of Pre-B-cell Leukemia Homeobox 1.
J Biol Chem
; 291(18): 9617-28, 2016 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26971355
18.
Nitroxoline shows antimyeloma activity by targeting the TRIM25/p53 axle.
Anticancer Drugs
; 28(4): 376-383, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28301380
19.
The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex.
J Pharmacol Sci
; 134(4): 197-202, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28779993
20.
A novel STAT3 inhibitor negatively modulates platelet activation and aggregation.
Acta Pharmacol Sin
; 38(5): 651-659, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28260800